BDBM22579 AICAR::Aminoimidazole-4-carboxamide ribonucleotide::CHEMBL483849::ZMP::{[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

SMILES NC(=O)c1ncn([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)c1N

InChI Key InChIKey=NOTGFIUVDGNKRI-UUOKFMHZSA-N

Data  3 IC50  2 Kd

PDB links: 10 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22579   

TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL

LigandBDBM22579(AICAR | Aminoimidazole-4-carboxamide ribonucleotid...)Copy SMILESCopy InChI

Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against AICAR formyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLKEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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